Business services
We offer services for institutions and companies wishing to carry out biological tests on their products or prototypes, according to European Certifications or by developing a tailored experimental protocol.
Our Offer includes:
Quantitative tests for the evaluation of the virucidal activity of new devices, prototypes or chemical agents designed by companies for sanitizing purposes:
Test for the evaluation of the virucidal activity of devices, prototypes or chemical agents on viruses deposited on surfaces or fabrics;
Test for evaluation of the virucidal activity of devices, prototypes or chemical agents on nebulized viruses;
Further specific tests upon customer request.
Quantitative tests for the evaluation of antiviral activity and cytotoxicity of molecules on cell lines or tissues in 3D cultures:
Cell viability and cytotoxicity assays (on cell lines and 3D cultures);
Infectivity reduction assay and virus yield reduction assay (on cell lines and 3D cultures);
Assays for evaluating the synergistic activity of two or more molecules;
Assays for evaluating the onset of viral resistance to the molecule under examination;
Specific antiviral assays for the study of the antiviral mechanism of action of the molecule in question;
Further antiviral assays at the request of the customer.
The Laboratory has a large panel of more than 30 human and animal viruses to perform biological tests
Human respiratory viruses
Human rhinovirus type A (HRV-A)
Human rhinovirus type B (HRV-B)
Respiratory syncytial virus type A (RSV-A)
Influenza virus type A H1N1 (FluV-A H1N1)
Influenza virus type A H3N2 (FluV-A H3N2)
Influenza virus type B (FluV-B)
Human coronavirus OC43 (HCoV OC43)
Human coronavirus 229E (HCoV 229E)
Adenovirus (AdV5)
Herpetic viruses
Herpes simplex virus type 1 (HSV-1)
Herpes simplex virus type 2 (HSV-2)
Human cytomegalovirus (HCMV)
Varicella Zoster virus (VZV)
Fecal-oral route transmitted viruses
Human rotavirus strain Wa (HRoV Wa)
Human rotavirus strain DS-1 (HRoV DS-1)
Human rotavirus strain WI61 (HRoV WI61)
Human rotavirus strain HRV408 (HRoV 408)
Human rotavirus strain HRV248 (HRoV 248)
Emerging viruses transmitted by arthropods
Zika virus (ZIKV) strain 1947 Uganda MR766
Zika virus strain (ZIKV) 2013 French Polynesia HPF2013
Usutu virus (USUV) strain 3345 (isolate: Arb276)
Pseudovirions
Pseudovirions of human papillomavirus types 16 and 18 (HPV-16, HPV-18) e bovine papillomavirus (BPV)
Pseudovirions of SARS-CoV-2
Animal viruses
Porcine rotavirus strain CRW-8 (HRoV CRW-8)
Bovine rotavirus strain NCDV (HRoV NCDV)
Simian rotavirus strain SA11 (HRoV SA11)
Murine norovirus CW1 (MNV-1)
Murine herpes virus (MHV-68)
Vesicular stomatitis virus (VSV)
Vaccinia virus (VACV)
Bovine viral diarrhea virus 1 (BVD)
Suid herpesvirus 1 (PRV)
Feline calicivirus (F-9)
Other viruses can be tested upon customer request
Cells infected by coronavirus OC43 visualized in confocal microscopy via immunofluorescence (cell nuclei in blu, OC43 nucleoprotein in red)
Transmission electron microscopy image of herpes simplex virus type 2 virions in the nucleus of an infected cell
Cells infected with human rotavirus coloured by immunostaining at the optical microscope